Everytime I hear this song, I think of Naruto and Sasuke of off the anime Naruto. Like you guys, I think in some cases it could be a relationship between a guy and a girl. But I also think it could be about 2 friends that have come a long way on a journey or a quest, gotten into a tough spot, and are starting to lose hope in one another. It sounds cheesy, but anyone who watches Naruto will probably understand what I'm saying.
~Falloutwolf96.