This song is about the destruction of The Self. It's all about "swinging from the chandelier", which literally means to have sex with as many people as possible. She is also involved with heavy drinking, and she has too many times tried to escaping the pain in her life, so now she has given it all up. This is a song about social suicide; a song about how to completely ruin everything which evolves from an identity. It's about self-destruction, a beautiful song of how to escape life by doing unhealthy things to your body and your mental health then completely disappearing from the surface of the earth.
It's a song of a person who is having a breakdown and finally putting an end to it with a solution which ends with taking her own life. Putting an end to her miser-ability after engaging in promiscuity and being infected with AIDS.