The song title is more or less a direct quote from "The Good Son", which is a movie from the 90's about a kid who turns out to be a psychopath. He creates a lifesized doll who he names "Mr. Highway", takes him to a highway overpass, and sits him on the edge of the bridge. Turning to his cousin, who has no idea what's about to happen, he says, "Poor Mr. Highway, he's thinking about the end. He's had enough of this terrible life." grins, and pushes the doll off the bridge into oncoming traffic, causing a massive accident.